<div dir="ltr">Hi Nick,<div>the quote was already for three samples, and you already approved it. So nothing has changed, I just had to correct the error.</div><div>-Borries</div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Tue, Sep 26, 2023 at 11:20 AM Harrington, Nick (Nicholas) J <<a href="mailto:NJHARRINGTON@beckman.com">NJHARRINGTON@beckman.com</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div class="msg2763458744256787336">





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<p class="MsoNormal"><span style="font-size:11pt">3 samples are fine with me.  Please provide an updated quote.<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:11pt"><u></u> <u></u></span></p>
<p class="MsoNormal"><span style="font-size:11pt">Thanks,<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:11pt">Nick<u></u><u></u></span></p>
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<p class="MsoNormal"><span style="font-size:9pt;font-family:Arial,sans-serif;color:red">Nick Harrington
</span><span style="font-size:9pt;font-family:Arial,sans-serif;color:black">| Sales Specialist</span><span style="font-size:11pt"><u></u><u></u></span></p>
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<p class="MsoNormal"><b><span style="font-size:11pt">From:</span></b><span style="font-size:11pt"> Borries Demeler <<a href="mailto:demeler@gmail.com" target="_blank">demeler@gmail.com</a>>
<br>
<b>Sent:</b> Monday, September 25, 2023 2:48 PM<br>
<b>To:</b> Bird, Sophia <<a href="mailto:sophia.bird@uleth.ca" target="_blank">sophia.bird@uleth.ca</a>><br>
<b>Cc:</b> Harrington, Nick (Nicholas) J <<a href="mailto:NJHARRINGTON@beckman.com" target="_blank">NJHARRINGTON@beckman.com</a>>; Samantha R. Tracy <<a href="mailto:Samantha@clene.com" target="_blank">Samantha@clene.com</a>>; <a href="mailto:demelerlab@biophysics.uleth.ca" target="_blank">demelerlab@biophysics.uleth.ca</a><br>
<b>Subject:</b> Re: EXTERNAL: Gold nanoparticles<u></u><u></u></span></p>
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<p class="MsoNormal"><u></u> <u></u></p>
<div>
<p class="MsoNormal"><span style="font-size:1pt;color:white">Hi Samantha, Sophia and Nick: I found a small correction - I believe we discussed three, not two, different samples to be compared to prove effectiveness of AUC
 on these samples. So please include all three :) Thanks, -Borries On Sun, Sep 24,
<u></u><u></u></span></p>
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<pre style="white-space:pre-wrap"><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">Hi Samantha, Sophia and Nick:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">I found a small correction - I believe we discussed three, not two, different samples to be compared to prove effectiveness of AUC on these samples.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">So please include all three :)<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">Thanks, -Borries<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">On Sun, Sep 24, 2023 at 12:18:46AM +0000, Bird, Sophia wrote:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Hello all,<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> I am a student in Bo's lab and just wanted to provide some shipping information. To avoid any issues with customs, samples could be sent to the University of Montana and Bo can pick them up by this Thursday. Bruce Bowler can receive them for us, his contact information is below:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> University of Montana<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> 32 Campus Dr<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Missoula, MT 59812<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Attn: Bruce Bowler, Chemistry and Biochemistry (Chem 310)<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Phone: 406 243-6114<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> I've attached a commercial invoice with the receiver information. Again, the experimental design was updated to outline the plan. Please ensure that 15 mL of buffer and the two 1.5 mL aliquots at 1 OD 525 nm are provided.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Let me know if there are any questions!<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Thanks,<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Sophia<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> ________________________________<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> From: Demelerlab <<a href="mailto:demelerlab-bounces@biophysics.uleth.ca" target="_blank">demelerlab-bounces@biophysics.uleth.ca</a>> on behalf of Harrington, Nick (Nicholas) J <<a href="mailto:NJHARRINGTON@beckman.com" target="_blank">NJHARRINGTON@beckman.com</a>><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Sent: 19 September 2023 10:33<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> To: Borries Demeler <<a href="mailto:demeler@gmail.com" target="_blank">demeler@gmail.com</a>>; Samantha R. Tracy <<a href="mailto:Samantha@clene.com" target="_blank">Samantha@clene.com</a>>; <a href="mailto:demelerlab@biophysics.uleth.ca" target="_blank">demelerlab@biophysics.uleth.ca</a> <<a href="mailto:demelerlab@biophysics.uleth.ca" target="_blank">demelerlab@biophysics.uleth.ca</a>><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Subject: Re: [Demelerlab] EXTERNAL: Gold nanoparticles<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Caution: This email was sent from someone outside of the University of Lethbridge. Do not click on links or open attachments unless you know they are safe. Suspicious emails should be forwarded to <a href="mailto:phishing@uleth.ca" target="_blank">phishing@uleth.ca</a>.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Thanks Borries for leading the call yesterday and apologies to the group for my unexpected absence due to dental work and delays at their office.  Ugh.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> The proposed experimentation, number of samples, and expected output is clear and fits with our expectations.  Please have a quotation put together and sent to my attention for review.  Once I have that, I will approve and we can move forward with sample shipping and subsequent analysis.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Thanks!<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Nick<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Confidential - Company Proprietary<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> From: Borries Demeler <<a href="mailto:demeler@gmail.com" target="_blank">demeler@gmail.com</a>><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Sent: Tuesday, September 19, 2023 11:58 AM<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> To: Samantha R. Tracy <<a href="mailto:Samantha@clene.com" target="_blank">Samantha@clene.com</a>>; <a href="mailto:demelerlab@biophysics.uleth.ca" target="_blank">demelerlab@biophysics.uleth.ca</a>; Harrington, Nick (Nicholas) J <<a href="mailto:NJHARRINGTON@beckman.com" target="_blank">NJHARRINGTON@beckman.com</a>><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Subject: Re: EXTERNAL: Gold nanoparticles<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Perfect, I reviewed the project request and I have most of the information I need to design the experiment. I was wondering if you could add a representative TEM image by uploading it in your LIMS account under "Supporting Files"<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> ZjQcmQRYFpfptBannerStart<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> This Message Is From an External Sender<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> This message came from outside your organization. Use caution when opening.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> ZjQcmQRYFpfptBannerEnd<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Perfect, I reviewed the project request and I have most of the information I need to design the experiment. I was wondering if you could add a representative TEM image by uploading it in your LIMS account under "Supporting Files" (button in the left bar). You can associate it with your project request. Also, if you know the expected range of particle sizes in nanometers that would help as well to predict the most suitable rotor speed, and would save some experimentation time. If you happen to have an absorbance spectrum down to 220 nm or so of a very dilute sample, you can upload that as well.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> As soon as I have approval from Nick to proceed, Sophia in our lab will send you shipping instructions. Please include at least 15 ml of buffer for these samples for dilutions.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Thanks! -Borries<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> On Tue, Sep 19, 2023 at 8:27 AM Samantha R. Tracy <<a href="mailto:Samantha@clene.com%3cmailto:Samantha@clene.com" target="_blank">Samantha@clene.com<mailto:Samantha@clene.com</a>>> wrote:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Hi Borries,<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> We have just filled out the project details to the best of our ability. If you have any follow up questions let me know.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Thanks,<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Samantha Tracy<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Research Engineer<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Clene Nanomedicine<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> This email may contain material that is confidential, privileged, and/or attorney work product for the sole use of the intended recipient. Any unauthorized review, use, or distribution is prohibited and may be unlawful.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> ________________________________<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> From: Borries Demeler <<a href="mailto:demeler@gmail.com%3cmailto:demeler@gmail.com" target="_blank">demeler@gmail.com<mailto:demeler@gmail.com</a>>><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Sent: Monday, September 18, 2023 5:51 PM<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> To: Raj, Rekha M <<a href="mailto:RRAJ@beckman.com%3cmailto:RRAJ@beckman.com" target="_blank">RRAJ@beckman.com<mailto:RRAJ@beckman.com</a>>>; Harrington, Nick (Nicholas) J <<a href="mailto:NJHARRINGTON@beckman.com%3cmailto:NJHARRINGTON@beckman.com" target="_blank">NJHARRINGTON@beckman.com<mailto:NJHARRINGTON@beckman.com</a>>>; Samantha R. Tracy <<a href="mailto:Samantha@clene.com%3cmailto:Samantha@clene.com" target="_blank">Samantha@clene.com<mailto:Samantha@clene.com</a>>>; Mikhail Merzliakov <<a href="mailto:Mikhail@clene.com%3cmailto:Mikhail@clene.com" target="_blank">Mikhail@clene.com<mailto:Mikhail@clene.com</a>>><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Cc: Aysha Demeler <<a href="mailto:aysha.demeler@uleth.ca%3cmailto:aysha.demeler@uleth.ca" target="_blank">aysha.demeler@uleth.ca<mailto:aysha.demeler@uleth.ca</a>>>; Elie Chdid <<a href="mailto:elie@aucsolutions.com%3cmailto:elie@aucsolutions.com" target="_blank">elie@aucsolutions.com<mailto:elie@aucsolutions.com</a>>>; Luc Roberts <<a href="mailto:luc@aucsolutions.com%3cmailto:luc@aucsolutions.com" target="_blank">luc@aucsolutions.com<mailto:luc@aucsolutions.com</a>>><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Subject: EXTERNAL: Gold nanoparticles<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Hi everyone,<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> as discussed today, in order to demonstrate the feasibility of the AUC method, and to contrast the results obtained from DLS, we plan to compare three samples of gold nanoparticles by sedimentation velocity. The goal is to demonstrate that AUC can pick up particle size distributions with much higher resolution than DLS and also can differentiate between different densities resulting from different metal core-hydration shell ratios.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> These questions have been previously evaluated by AUC in the following publications, two of which Aysha has contributed significantly already:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_25010012_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=Pr2sXjGYHcEs2Kh4yGtm-uv2zVtFIdk4iiUC26d7kgQ&e=%3e%3e" target="_blank">https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_25010012_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=Pr2sXjGYHcEs2Kh4yGtm-uv2zVtFIdk4iiUC26d7kgQ&e=><u></u><u></u></a></span></pre>
<pre><span class="m_2763458744256787336MsoHyperlink"><span style="font-size:11pt;font-family:Arial,sans-serif"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_25010012_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=Pr2sXjGYHcEs2Kh4yGtm-uv2zVtFIdk4iiUC26d7kgQ&e=%3e%3e" target="_blank">></a></span></span><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Demeler B, Nguyen TL, Gorbet GE, Schirf V, Brookes EH, Mulvaney P, El-Ballouli AO, Pan J, Bakr OM, Demeler AK, Hernandez Uribe BI, Bhattarai N, Whetten RL. Characterization of size, anisotropy, and density heterogeneity of nanoparticles by sedimentation velocity. Anal Chem. 2014 Aug 5;86(15):7688-95. doi: 10.1021/ac501722r. Epub 2014 Jul 18. PMID: 25010012; PMCID: PMC4144751.<<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_25010012_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=Pr2sXjGYHcEs2Kh4yGtm-uv2zVtFIdk4iiUC26d7kgQ&e=%3e%3e" target="_blank">https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_25010012_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=Pr2sXjGYHcEs2Kh4yGtm-uv2zVtFIdk4iiUC26d7kgQ&e=><u></u><u></u></a></span></pre>
<pre><span class="m_2763458744256787336MsoHyperlink"><span style="font-size:11pt;font-family:Arial,sans-serif"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_25010012_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=Pr2sXjGYHcEs2Kh4yGtm-uv2zVtFIdk4iiUC26d7kgQ&e=%3e%3e" target="_blank">></a></span></span><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> and:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Gorbet G, Devlin T, Hernandez Uribe BI, Demeler AK, Lindsey ZL, Ganji S, Breton S, Weise-Cross L, Lafer EM, Brookes EH, Demeler B. A parametrically constrained optimization method for fitting sedimentation velocity experiments. Biophys J. 2014 Apr 15;106(8):1741-50. doi: 10.1016/j.bpj.2014.02.022. PMID: 24739173; PMCID: PMC4008825.<<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_24739173_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=je35GYrI-3jZcUoJuixhZqJO35FJ0Y86rViw-Nz7HxY&e=%3e%3e" target="_blank">https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_24739173_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=je35GYrI-3jZcUoJuixhZqJO35FJ0Y86rViw-Nz7HxY&e=><u></u><u></u></a></span></pre>
<pre><span class="m_2763458744256787336MsoHyperlink"><span style="font-size:11pt;font-family:Arial,sans-serif"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_24739173_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=je35GYrI-3jZcUoJuixhZqJO35FJ0Y86rViw-Nz7HxY&e=%3e%3e" target="_blank">></a></span></span><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Core-shell studies by analytical ultracentrifugation have been done by us as well:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Walter J, Gorbet G, Akdas T, Segets D, Demeler B, Peukert W. 2D analysis of polydisperse core-shell nanoparticles using analytical ultracentrifugation. Analyst. 2016 Dec 19;142(1):206-217. doi: 10.1039/c6an02236g. PMID: 27934989; PMCID: PMC5167643.<<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_27934989_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=fWF0XIeLJLYPXBfDcwQZ581eJyQWsdQPfGmYGvXj8iw&e=%3e%3e" target="_blank">https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_27934989_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=fWF0XIeLJLYPXBfDcwQZ581eJyQWsdQPfGmYGvXj8iw&e=><u></u><u></u></a></span></pre>
<pre><span class="m_2763458744256787336MsoHyperlink"><span style="font-size:11pt;font-family:Arial,sans-serif"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__pubmed.ncbi.nlm.nih.gov_27934989_&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=fWF0XIeLJLYPXBfDcwQZ581eJyQWsdQPfGmYGvXj8iw&e=%3e%3e" target="_blank">></a></span></span><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> To proceed, we ask that the scientist in charge of this project creates a LIMS account in our LIMS server instance on this website:<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwIDaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=fHsQQ4-lq25VEM0aB9nl8LK9L-nqhPHnFx3eeZx4oyNYQR0kYlH6AT2lfRHp3_8x&s=V7Y_8KSTQs8lKUW2vuO1aA_ujowpCgvdQJU8Z8BU0tY&e=" target="_blank">https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwIDaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=fHsQQ4-lq25VEM0aB9nl8LK9L-nqhPHnFx3eeZx4oyNYQR0kYlH6AT2lfRHp3_8x&s=V7Y_8KSTQs8lKUW2vuO1aA_ujowpCgvdQJU8Z8BU0tY&e=</a><u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=chs-OgiINwPtfAmyiyuPn-ZnMhtxf0fz8b9O0r1Tg3c&e=%3e%3e" target="_blank">https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=chs-OgiINwPtfAmyiyuPn-ZnMhtxf0fz8b9O0r1Tg3c&e=><u></u><u></u></a></span></pre>
<pre><span class="m_2763458744256787336MsoHyperlink"><span style="font-size:11pt;font-family:Arial,sans-serif"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=chs-OgiINwPtfAmyiyuPn-ZnMhtxf0fz8b9O0r1Tg3c&e=%3e%3e" target="_blank">></a></span></span><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=chs-OgiINwPtfAmyiyuPn-ZnMhtxf0fz8b9O0r1Tg3c&e=%3e%3e" target="_blank">https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=chs-OgiINwPtfAmyiyuPn-ZnMhtxf0fz8b9O0r1Tg3c&e=><u></u><u></u></a></span></pre>
<pre><span class="m_2763458744256787336MsoHyperlink"><span style="font-size:11pt;font-family:Arial,sans-serif"><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__uslims.uleth.ca_uslims3-5FAUCCANADA_newaccount.php&d=DwMFaQ&c=9mghv0deYPYDGP-W745IEdQLV1kHpn4XJRvR6xMRXtA&r=ABy6E2p1lUDF_Nv0SrOTF281fkSdheTDlBdDP5aOa8w&m=0QAtnL0RCULIZuwls6omiHqL35tTkg-5LA8GuSl-Io_KnDO40lcsoXnQ_xeZEKwa&s=chs-OgiINwPtfAmyiyuPn-ZnMhtxf0fz8b9O0r1Tg3c&e=%3e%3e" target="_blank">></a></span></span><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> and create a project request ("Projects" button on the left bar) to get the ball rolling. Aysha will provide you with the shipping instructions and Luc or Elie will prepare a cost estimate for Nick to get a PO issued. We discussed obtaining ~2 ml of 1 OD at peak absorbance wavelength of three different samples to demonstrate that different answers can be obtained for each sample, and we may consider diluting the sample with the storage buffer (please provide 15 ml). Further details will be provided in the project request.<u></u><u></u></span></pre>
<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> <u></u><u></u></span></pre>
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<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Please let me know if you have any questions.<u></u><u></u></span></pre>
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<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Regards, -Borries<u></u><u></u></span></pre>
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<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> PRIVILEGED AND CONFIDENTIAL This electronic message, including all attachments, is intended solely for the use of the individual or entity named above, and may contain CONFIDENTIAL, PRIVILEGED, and/or TRADE SECRET INFORMATION. If you are not the intended recipient, you are hereby notified that any use, dissemination, distribution, or copying of this electronic message, including any attachments, is strictly prohibited. If you receive this electronic message in error, please notify the sender immediately. Please consider the environment before printing this e-mail.<u></u><u></u></span></pre>
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<pre><span style="font-size:11pt;font-family:Arial,sans-serif">> Please be advised that this email may contain confidential information. If you are not the intended recipient, please notify us by email by replying to the sender and delete this message. The sender disclaims that the content of this email constitutes an offer to enter into, or the acceptance of, any agreement; provided that the foregoing does not invalidate the binding effect of any digital or other electronic reproduction of a manual signature that is included in any attachment.<u></u><u></u></span></pre>
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<pre><span style="font-size:11pt;font-family:Arial,sans-serif"><u></u> <u></u></span></pre>
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