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Hello all,</div>
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Dr. Demeler, Walter and I all agreed a letter update is in order - I hope this finds everyone in glad preparations for the holidays!</div>
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<div class="elementToProof" style="margin: 0px;">Please remember everything disclosed below is only for those under NDA signed with Beckman.</div>
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<div style="margin: 0px;">What we need to do to progress the AUC Fluorescence project:</div>
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<div class="elementToProof" style="margin: 0px;">Beckman requires us to pass certain technical readiness levels to evaluate projects with our leadership. Anything that passes our first tollgate, "TG0," gets some degree of funding. We are still pre-TG0 for this
project. In order to pass TG0 we must:</div>
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<div class="elementToProof" style="margin: 0px;">Show technical feasibility for all parts of the project (e.g., lasers + detectors work as intended and can operate within an ultracentrifuge).</div>
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<div style="margin: 0px;">Show a compelling business case that is approved by leadership.</div>
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<div style="margin: 0px;">Current status within Beckman on the AUC Fluorescence project: </div>
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<div class="elementToProof" style="margin: 0px;">We have finally and happily secured the time of several engineers within Beckman. Having these engineers means that we now (for the first time) have people to:</div>
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<div style="margin: 0px;">Define design specifications / user requirements of a fluorescence detector (Our engineers have intimate knowledge of the existing AUC and the constraints of using its box + dimensions). </div>
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<div style="margin: 0px;"> Work on proving feasibility of the fluorescence detector if needed, then to design the detector (if we pass TG0), then to develop the detector for mass production (if we pass the next major tollgate, TG2).</div>
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<div class="elementToProof" style="margin: 0px;">Evaluate + work with partners such as yourselves who we can work with to conduct feasibility or other elements of design + development.</div>
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<div style="margin: 0px;">What's next?</div>
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<div style="margin: 0px;">We are working on a user requirements list right now.</div>
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<div class="elementToProof" style="margin: 0px;">We would love to present the user requirements to you in a few weeks (perhaps in January?), then to get a quote from you for what working on the project would cost + a time estimate.</div>
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<div style="margin: 0px;">What does this mean for the grants? </div>
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<div style="margin: 0px;">Nothing for the time being. For the first time, we have people to work on the formal Beckman process side of the project. We view this as a big win, but we are still not at the point that we have a formalized, fully funded Beckman
project. </div>
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<div style="margin: 0px;">To level set, funding a partner to help with feasibility or design of a project is not uncommon, but all such requests are approved on a one-off basis, and are not assumed to be funded (by contrast, fully funded projects at Beckman
have more discretion given to the project team).</div>
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Walter + I are happy to meet 1:1 with anyone who is interested in discussing more or with anyone who has concerns. We want to make sure we do right by everyone who has been involved. Walter has volunteered to be available the Monday and Tuesday after Christmas.
Of course, if those times don't work for you and you'd like to meet. We will be happy to make time.</div>
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Thank you and have a great holiday season!</div>
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Abe + Walter</div>
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